一、主要研究方向
皮肤光损伤
二、个人简历
2018年取得韩国庆熙大学生命科学院生物技术学博士学位，同年，入职药学院药理学教研室。主持安徽省自然科学基金、教育厅中青年教师培养行动项目、教育厅自然科学重点项目、留学回国人员创新创业项目等省部级科研/人才项目4项；以第一作者或通讯作者发表SCI论文十余篇。
三、主持科研/教学项目
1.安徽省自然科学基金青年项目，2008085QH417，《探究miR-221/222 对脂肪干细胞向内皮细胞分化的调控作用及作用机制》，2020.07~2022.07，10万，主持；
2.安徽省留学回国人员创新创业项目，2020LCX0124，《基于miR-138/SIRT1信号通路探讨ADSCs外泌体 lncRNA H19 对紫外线辐射皮肤光老化的调控作用》，2020.06~2022.06，5万，主持；
3.安徽省教育厅中青年教师培养行动项目优秀青年教师培育项目，YQYB2024040，《SLC25A51转运体在紫外线辐射诱导皮肤 DNA 损伤中的作用研究》，2025.01~2026.12，5万，主持；
4. 安徽省教育厅高校自然科学重点项目，2024AH051242，《从干预氧化应激及脯氨酸代谢角度探讨β-烟酰胺单核苷酸（NMN）逆转皮肤光老化分子机制》，2024.05-2026.05，10万，主持。
四、代表性成果（论文/专利/专著等）
1.Yue Zhang, Chen Ai, Fangzhou Huang, Ji‑Li Zhao, Yixin Ling, Weijing Chen, Zhenzhu Li, Yu Wang, Fei Gao, Siqi Li, Wei Gao*, Yu‑shuai Wang*.β‑Nicotinamide mononucleotide blocks UVB‑induced collagen reduction via regulation of ROS/MAPK/AP‑1 and stimulation of mitochondrial proline biosynthesis.Photochemical & Photobiological Sciences. 2025, 24:293-306.
2.Wei Gao, Limin Yuan, Yue Zhang, Fangzhou Huang, Chen Ai, Tianci Lv, Jiale Chen, Hui Wang, Yixin Ling, Yu-shuai Wang*. miR-1246-overexpressing exosomes improve UVB-induced photoaging by activating autophagy via suppressing GSK3β. Photochemical & Photobiological Sciences. 2024, 23(5):957-972.
3.Gao Wei, Yuan Li-Min, Zhang Yue, Huang Fang-Zhou, Gao Fei, Li Jian, Xu Feng, Wang Hui, Wang Yu-Shuai*. miR-1246-overexpressing exosomes suppress UVB-induced photoaging via regulation of TGF-β/Smad and attenuation of MAPK/AP-1 pathway. Photochemical & Photobiological Sciences, 2023, 22(1): 135-146.
4.Wei Gao, Yue Zhang, Limin Yuan, Fangzhou Huang, Yu-shuai Wang*. Long Non-coding RNA H19 Overexpressing Exosomes Ameliorates UVB-induced Photoaging by Upregulating SIRT1 via Sponging miR-138. Photochemistry and Photobiology. 2023, 99(6) :1456–1467.
5.Gao Wei, Yuan Limin, Zhang Yue, Si Yue, Wang Xuqing, Lv Tianci, Wang Yu-Shuai*. miR-221/222 Promote Endothelial Differentiation of Adipose-Derived Stem Cells by Regulation of PTEN/PI3K/AKT/mTOR Pathway. Appl Biochem Biotechnol. 2023, 195(7):4196–4214.
6.Wei Gao，Shengdao Zheng，Eunson Hwang，Tae-hoo Yi*，Yu-shuai Wang*. Effects of phenylethanol glycosides from Orobanche cernua Loefling on UVB-Induced skin photodamage: a comparative study. Photochemical & Photobiological Sciences. 2021, 20, 599–614.
7.Wei Gao; Xiu Wang; Yue Si; Jinlong Pang; Hao Liu; Shanshan Li; Qi Ding; Yu-shuai Wang*. Exosome Derived from ADSCs Attenuates Ultraviolet B-mediated Photoaging in Human Dermal Fibroblasts, Photochemistry and photobiology. 2021, 97(4): 795-804.
